LFNG Antibody (Center) Blocking Peptide

Product Overview

• Article Name: LFNG Antibody (Center) Blocking Peptide
• Biozol Catalog Number: ABT-BP9524C
• Supplier Catalog Number: BP9524c
• Alternative Catalog Number: ABT-BP9524C-500UG
• Manufacturer: Abcepta
• Category: Proteine/Peptide
• Alternative Names: Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe, O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase, LFNG

Product Description

LFNG belongs to evolutionarily conserved glycosyltransferases that act in the Notch signaling pathway to define boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose-specific beta-1,3-N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling. This protein is predicted to be a single-pass type II Golgi membrane protein but it may also be secreted and proteolytically processed like the related proteins in mouse and Drosophila (PMID: 9187150).

Product Properties

• NCBI: 3955
• UniProt: Q8NES3
• Form: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.