Fludarabine, CAS [[21679-14-1]]

Produktübersicht

• Artikelname: Fludarabine, CAS [[21679-14-1]]
• Artikelnummer: AMO-M2028
• Hersteller Artikelnummer: M2028
• Alternativnummer: AMO-M2028-5MG,AMO-M2028-10MG,AMO-M2028-25MG
• Hersteller: Abmole Bioscience
• Kategorie: Biochemikalien
• Alternative Synonym: Fludara, NSC 118218, Fludarabinum, F-ara-A

Produktbeschreibung

Fludarabine (NSC 118218) is a STAT1 activation inhibitor and a DNA synthesis inhibitor. Fludarabine inhibits DNA synthesis by interfering with ribonucleotide reductase and DNA polymerase. Fludarabine markedly inhibited VSMC proliferation in cell culture. Fludarabine also induces significant reduction of STAT-1 phosphorylation, whereas it does not change JAK2 activation. Fludarabine exhibits antiproliferative activity (IC50 = 1.54 µM in RPMI cells) and triggers apoptosis through increasing Bax and decreasing Bid, XIAP and survivin expression.

Produkteigenschaften

• Molekulargewicht: 285.23
• Reinheit: 100.00%
• CAS Nummer: [21679-14-1]
• Formel: C10H12FN5O4
• Target-Kategorie: STAT