Vepdegestrant (ARV-471), CAS [[2229711-68-4]]

Produktübersicht

• Artikelname: Vepdegestrant (ARV-471), CAS [[2229711-68-4]]
• Artikelnummer: AMO-M21158
• Hersteller Artikelnummer: M21158
• Alternativnummer: AMO-M21158-1MG,AMO-M21158-5MG,AMO-M21158-10MG
• Hersteller: Abmole Bioscience
• Kategorie: Biochemikalien
• Alternative Synonym: ARV471, PF-07850327

Produktbeschreibung

Vepdegestrant (ARV-471) is an oral estrogen receptor PROTAC protein degrader for breast cancer.ARV-471 is a heterobifunctional molecule that promotes the interaction between estrogen receptor alpha and intracellular E3 ligase complexes.ARV-471 causes ubiquitination and subsequent degradation of the estrogen receptor via the proteasome.ARV-471 potently degrades ER-positive The ER in breast cancer cell lines is potently degraded by ARV-471 with a DC50 value of approximately 2 nM.

Produkteigenschaften

• Molekulargewicht: 723.9
• Reinheit: >99%
• CAS Nummer: [2229711-68-4]
• Formel: C45H49N5O4
• Target-Kategorie: PROTAC