Vepdegestrant (ARV-471), CAS [[2229711-68-4]]

Product Overview

• Article Name: Vepdegestrant (ARV-471), CAS [[2229711-68-4]]
• Biozol Catalog Number: AMO-M21158
• Supplier Catalog Number: M21158
• Alternative Catalog Number: AMO-M21158-1MG,AMO-M21158-5MG,AMO-M21158-10MG
• Manufacturer: Abmole Bioscience
• Category: Biochemikalien
• Alternative Names: ARV471, PF-07850327

Product Description

Vepdegestrant (ARV-471) is an oral estrogen receptor PROTAC protein degrader for breast cancer.ARV-471 is a heterobifunctional molecule that promotes the interaction between estrogen receptor alpha and intracellular E3 ligase complexes.ARV-471 causes ubiquitination and subsequent degradation of the estrogen receptor via the proteasome.ARV-471 potently degrades ER-positive The ER in breast cancer cell lines is potently degraded by ARV-471 with a DC50 value of approximately 2 nM.

Product Properties

• Molecular Weight: 723.9
• Purity: >99%
• CAS Number: [2229711-68-4]
• Formula: C45H49N5O4
• Target: PROTAC