Picropodophyllin (AXL1717), CAS [[477-47-4]]

Produktübersicht

• Artikelname: Picropodophyllin (AXL1717), CAS [[477-47-4]]
• Artikelnummer: AMO-M2411
• Hersteller Artikelnummer: M2411
• Alternativnummer: AMO-M2411-1MG,AMO-M2411-5MG,AMO-M2411-10MG,AMO-M2411-50MG
• Hersteller: Abmole Bioscience
• Kategorie: Biochemikalien
• Alternative Synonym: Picropodophyllotoxin, CAS 17434-18-3, PPP

Produktbeschreibung

AXL1717 (picropodophyllin, Picropodophyllotoxin, PPP) is a non-competitive, potent, and specific inhibitor of IGF-1Ralpha/beta with IC50 of 1 nM. Picropodophyllin binds to the intracellular tyrosine kinase domain of IGF-1R, inducing a conformational shift to an inactive state, thereby effectively inhibiting its autophosphorylation and downstream signal transduction.

Produkteigenschaften

• Molekulargewicht: 414.41
• Reinheit: >99%
• CAS Nummer: [477-47-4]
• Formel: C22H22O8
• Target-Kategorie: IGF-1R