Teprotumumab, CAS [[1036734-93-6]]

Produktübersicht

• Artikelname: Teprotumumab, CAS [[1036734-93-6]]
• Artikelnummer: AMO-M24540
• Hersteller Artikelnummer: M24540
• Alternativnummer: AMO-M24540-100UG
• Hersteller: Abmole Bioscience
• Kategorie: Biochemikalien
• Alternative Synonym: RV001, R1507

Produktbeschreibung

Teprotumumab (RV001, R1507) is a first-in-class IGF-1 receptor (IGF-1R) blocking human monoclonal antibody. Teprotumumab binds to the ligand binding extracellular alpha-subunit domain of IGF-1R. Teprotumumab inhibits TSH and IGF-1 action in fibrocytes. Teprotumumab attenuates TSH-dependent IL-6 and IL-8 expression and Akt phosphorylation. Teprotumumab can be used for thyroid-associated ophthalmopathy research.

Produkteigenschaften

• Reinheit: 99.0%
• CAS Nummer: [1036734-93-6]
• Target-Kategorie: IGF-1R