Teprotumumab, CAS [[1036734-93-6]]

Product Overview

• Article Name: Teprotumumab, CAS [[1036734-93-6]]
• Biozol Catalog Number: AMO-M24540
• Supplier Catalog Number: M24540
• Alternative Catalog Number: AMO-M24540-100UG
• Manufacturer: Abmole Bioscience
• Category: Biochemikalien
• Alternative Names: RV001, R1507

Product Description

Teprotumumab (RV001, R1507) is a first-in-class IGF-1 receptor (IGF-1R) blocking human monoclonal antibody. Teprotumumab binds to the ligand binding extracellular alpha-subunit domain of IGF-1R. Teprotumumab inhibits TSH and IGF-1 action in fibrocytes. Teprotumumab attenuates TSH-dependent IL-6 and IL-8 expression and Akt phosphorylation. Teprotumumab can be used for thyroid-associated ophthalmopathy research.

Product Properties

• Purity: 99.0%
• CAS Number: [1036734-93-6]
• Target: IGF-1R