Resmetirom (MGL-3196), CAS [[920509-32-6]]

Produktübersicht

• Artikelname: Resmetirom (MGL-3196), CAS [[920509-32-6]]
• Artikelnummer: AMO-M3184
• Hersteller Artikelnummer: M3184
• Alternativnummer: AMO-M3184-1MG,AMO-M3184-2MG,AMO-M3184-5MG,AMO-M3184-10MG,AMO-M3184-25MG,AMO-M3184-50MG
• Hersteller: Abmole Bioscience
• Kategorie: Biochemikalien
• Alternative Synonym: VIA-3196, MGL-3196

Produktbeschreibung

Resmetirom (MGL-3196, VIA-3196, resmetirom) is a potentially first-in-class, liver-targeted, orally active, selective thyroid hormone receptor (THR)-beta agonist with an EC50 value of 0.21 µM. Resmetirom avoids the activation of THR-alpha receptors that mediate thyroid hormone activity outside of the liver, including the heart and bone. Resmetirom avoids the activation of THR-alpha receptors that mediate extrahepatic (including cardiac and skeletal) thyroid hormone activity and can be used in studies of non-alcoholic steatohepatitis (NASH).

Produkteigenschaften

• Molekulargewicht: 435.22
• Reinheit: 99.87%
• CAS Nummer: [920509-32-6]
• Formel: C17H12Cl2N6O4
• Target-Kategorie: Thyroid Hormone Receptor