PK11007 is a mild thiol alkylating agent with anticancer activity that stabilizes p53 through selective alkylation of two surface-exposed cysteines without affecting its DNA-binding activity. It also induces death of mutant p53 cancer cells by increasing reactive oxygen species (ROS) levels.
Molekulargewicht:
427.86
Reinheit:
>98.5%
CAS Nummer:
[874146-69-7]
Formel:
C15H11ClFN5O3S2
Target-Kategorie:
p53
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
