PK11007 is a mild thiol alkylating agent with anticancer activity that stabilizes p53 through selective alkylation of two surface-exposed cysteines without affecting its DNA-binding activity. It also induces death of mutant p53 cancer cells by increasing reactive oxygen species (ROS) levels.
Molecular Weight:
427.86
Purity:
>98.5%
CAS Number:
[874146-69-7]
Formula:
C15H11ClFN5O3S2
Target:
p53
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