A-582941 dihydrochloride is a potent, selective, partial agonist of alpha7 nAChR across the blood-brain barrier, with Ki values of 10.8 nM in rat meninges and 16.7 nM in human frontal cortex.Additionally, A-582941 dihydrochloride binds to human 5- and 5HT3 receptors with a Ki value of 150 nM. In addition, A-582941 dihydrochloride can bind to human 5- HT3 receptors at a Ki value of 150 nM. A-582941 dihydrochloride can be used in studies of various neurodegenerative diseases and cognitive deficits.
Molekulargewicht:
353.29
Reinheit:
>99.0%
CAS Nummer:
[848591-90-2]
Formel:
C17H22Cl2N4
Target-Kategorie:
AChR/AChE
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