A-582941 dihydrochloride is a potent, selective, partial agonist of alpha7 nAChR across the blood-brain barrier, with Ki values of 10.8 nM in rat meninges and 16.7 nM in human frontal cortex.Additionally, A-582941 dihydrochloride binds to human 5- and 5HT3 receptors with a Ki value of 150 nM. In addition, A-582941 dihydrochloride can bind to human 5- HT3 receptors at a Ki value of 150 nM. A-582941 dihydrochloride can be used in studies of various neurodegenerative diseases and cognitive deficits.
Molecular Weight:
353.29
Purity:
>99.0%
CAS Number:
[848591-90-2]
Formula:
C17H22Cl2N4
Target:
AChR/AChE
* VAT and and shipping costs not included. Errors and price changes excepted
