Recombinant Human BMPRIA/ALK-3/CD292 Protein (HEK293, C-His)
Artikelnummer:
AMO-M55622
Hersteller Artikelnummer:
M55622
Alternativnummer:
AMO-M55622-100UG
Hersteller:
Abmole Bioscience
Kategorie:
Biochemikalien
Alternative Synonym:
Bone Morphogenetic Protein Receptor type IA, Activin receptor-Like Kinase 3, ACVRLK3
BMPR1A/ALK-3/CD292 protein is expressed in the epithelium during branching morphogenesis. It is a type I receptor for bone morphogenetic proteins (BMPs) which belong to the transforming growth factor beta (TGF-beta) superfamily. BMPR1A/ALK-3 plays an essential role in the formation of embryonic ventral abdominal wall, and abrogation of BMP signaling activity due to gene mutations in its signaling components could be one of the underlying causes of omphalocele at birth. The type IA BMP receptor, ALK-3 was specifically required at mid-gestation for normal development of the trabeculae, compact myocardium, interventricular septum, and endocardial cushion.
Reinheit:
>90%, Endotoxin < 1 EU/µg
CAS Nummer:
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Target-Kategorie:
Cytokines and Growth Factors
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