Recombinant Human BMPRIA/ALK-3/CD292 Protein (HEK293, C-His)
Biozol Catalog Number:
AMO-M55622
Supplier Catalog Number:
M55622
Alternative Catalog Number:
AMO-M55622-100UG
Manufacturer:
Abmole Bioscience
Category:
Biochemikalien
Alternative Names:
Bone Morphogenetic Protein Receptor type IA, Activin receptor-Like Kinase 3, ACVRLK3
BMPR1A/ALK-3/CD292 protein is expressed in the epithelium during branching morphogenesis. It is a type I receptor for bone morphogenetic proteins (BMPs) which belong to the transforming growth factor beta (TGF-beta) superfamily. BMPR1A/ALK-3 plays an essential role in the formation of embryonic ventral abdominal wall, and abrogation of BMP signaling activity due to gene mutations in its signaling components could be one of the underlying causes of omphalocele at birth. The type IA BMP receptor, ALK-3 was specifically required at mid-gestation for normal development of the trabeculae, compact myocardium, interventricular septum, and endocardial cushion.
Purity:
>90%, Endotoxin < 1 EU/µg
CAS Number:
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Target:
Cytokines and Growth Factors
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