(R)-NX-2127, CAS [[3024312-52-2]]

Produktübersicht

• Artikelname: (R)-NX-2127, CAS [[3024312-52-2]]
• Artikelnummer: AMO-M55647
• Hersteller Artikelnummer: M55647
• Alternativnummer: AMO-M55647-1MG,AMO-M55647-5MG,AMO-M55647-10MG,AMO-M55647-25MG
• Hersteller: Abmole Bioscience
• Kategorie: Biochemikalien
• Alternative Synonym: compound 28

Produktbeschreibung

(R)-NX-2127 (compound 28) is a first-in-class, orally bioavailable Brutons Tyrosine Kinase (Btk) degrader. (R)-NX-2127 mediates the degradation of transcription factors IKZF1 and IKZF3 through molecular glue interactions with the cereblon E3 ubiquitin ligase complex. NX-2127 degrades common BTK resistance mutants, including BTKC481S.

Produkteigenschaften

• Molekulargewicht: 719.83
• Reinheit: 99.76%
• CAS Nummer: [3024312-52-2]
• Formel: C39H45N9O5
• Target-Kategorie: BTK