(R)-NX-2127, CAS [[3024312-52-2]]

Product Overview

• Article Name: (R)-NX-2127, CAS [[3024312-52-2]]
• Biozol Catalog Number: AMO-M55647
• Supplier Catalog Number: M55647
• Alternative Catalog Number: AMO-M55647-1MG,AMO-M55647-5MG,AMO-M55647-10MG,AMO-M55647-25MG
• Manufacturer: Abmole Bioscience
• Category: Biochemikalien
• Alternative Names: compound 28

Product Description

(R)-NX-2127 (compound 28) is a first-in-class, orally bioavailable Brutons Tyrosine Kinase (Btk) degrader. (R)-NX-2127 mediates the degradation of transcription factors IKZF1 and IKZF3 through molecular glue interactions with the cereblon E3 ubiquitin ligase complex. NX-2127 degrades common BTK resistance mutants, including BTKC481S.

Product Properties

• Molecular Weight: 719.83
• Purity: 99.76%
• CAS Number: [3024312-52-2]
• Formula: C39H45N9O5
• Target: BTK