SC 144 hydrochloride, CAS [[917497-70-2]]

Produktübersicht

• Artikelname: SC 144 hydrochloride, CAS [[917497-70-2]]
• Artikelnummer: AMO-M7273
• Hersteller Artikelnummer: M7273
• Alternativnummer: AMO-M7273-5MG,AMO-M7273-10MG,AMO-M7273-25MG
• Hersteller: Abmole Bioscience
• Kategorie: Biochemikalien

Produktbeschreibung

SC144 hydrochloride is the first oral active GP130 (IL6-beta) inhibitor. SC144 hydrochloride binds gp130, inducing phosphorylation (S782) and deglycosylation of GP130, eliminating Stat3 phosphorylation and nuclear translocation, and further inhibiting the expression of downstream target genes. SC144 hydrochloride inhibited signal transduction induced by GP130 ligand. SC144 hydrochloride induces apoptosis of human ovarian cancer cells.

Produkteigenschaften

• Molekulargewicht: 358.76
• Reinheit: >98%
• CAS Nummer: [917497-70-2]
• Formel: C16H11FN6O.HCl
• Target-Kategorie: IL Receptor/Related