SC 144 hydrochloride, CAS [[917497-70-2]]

Product Overview

• Article Name: SC 144 hydrochloride, CAS [[917497-70-2]]
• Biozol Catalog Number: AMO-M7273
• Supplier Catalog Number: M7273
• Alternative Catalog Number: AMO-M7273-5MG,AMO-M7273-10MG,AMO-M7273-25MG
• Manufacturer: Abmole Bioscience
• Category: Biochemikalien

Product Description

SC144 hydrochloride is the first oral active GP130 (IL6-beta) inhibitor. SC144 hydrochloride binds gp130, inducing phosphorylation (S782) and deglycosylation of GP130, eliminating Stat3 phosphorylation and nuclear translocation, and further inhibiting the expression of downstream target genes. SC144 hydrochloride inhibited signal transduction induced by GP130 ligand. SC144 hydrochloride induces apoptosis of human ovarian cancer cells.

Product Properties

• Molecular Weight: 358.76
• Purity: >98%
• CAS Number: [917497-70-2]
• Formula: C16H11FN6O.HCl
• Target: IL Receptor/Related