INT-777, CAS [[1199796-29-6]]
Artikelnummer:
AMO-M9055
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| Artikelname: | INT-777, CAS [[1199796-29-6]] |
| Artikelnummer: | AMO-M9055 |
| Hersteller Artikelnummer: | M9055 |
| Alternativnummer: | AMO-M9055-1MG,AMO-M9055-2MG,AMO-M9055-5MG,AMO-M9055-10MG,AMO-M9055-25MG |
| Hersteller: | Abmole Bioscience |
| Kategorie: | Biochemikalien |
| Alternative Synonym: | S-EMCA |
| INT-777 is a potent TGR5 agonist with EC50 of 0.82 µM. In animal models, INT-777 alleviates liver injury by activating TGR5, thereby increasing bile flow and reducing bile acid synthesis. TGR5 signalling mediated by INT-777 induces the release of GLP-1 (glucagon-like peptide-1), improving liver and pancreatic function in obese mice. |
| Molekulargewicht: | 450.65 |
| Reinheit: | 98.29% |
| CAS Nummer: | [1199796-29-6] |
| Formel: | C27H46O5 |
| Target-Kategorie: | GPCR19/TGR5 |
