INT-777, CAS [[1199796-29-6]]

Product Overview

• Article Name: INT-777, CAS [[1199796-29-6]]
• Biozol Catalog Number: AMO-M9055
• Supplier Catalog Number: M9055
• Alternative Catalog Number: AMO-M9055-1MG,AMO-M9055-2MG,AMO-M9055-5MG,AMO-M9055-10MG,AMO-M9055-25MG
• Manufacturer: Abmole Bioscience
• Category: Biochemikalien
• Alternative Names: S-EMCA

Product Description

INT-777 is a potent TGR5 agonist with EC50 of 0.82 µM. In animal models, INT-777 alleviates liver injury by activating TGR5, thereby increasing bile flow and reducing bile acid synthesis. TGR5 signalling mediated by INT-777 induces the release of GLP-1 (glucagon-like peptide-1), improving liver and pancreatic function in obese mice.

Product Properties

• Molecular Weight: 450.65
• Purity: 98.29%
• CAS Number: [1199796-29-6]
• Formula: C27H46O5
• Target: GPCR19/TGR5