NDI-091143, CAS [[2375840-87-0]]

Artikelnummer: AMO-M9587
Artikelname: NDI-091143, CAS [[2375840-87-0]]
Artikelnummer: AMO-M9587
Hersteller Artikelnummer: M9587
Alternativnummer: AMO-M9587-2MG,AMO-M9587-5MG,AMO-M9587-10MG,AMO-M9587-25MG
Hersteller: Abmole Bioscience
Kategorie: Biochemikalien
NDI-091143 is a novel potent inhibitor of human ATP-citrate lyase with an IC50 of 2.1 nM (ADP-Glo assay), a Ki of 7.0 nM and a Kd of 2.2 nM. NDI-091143 inhibits ACLY catalysis allosterically, by stabilizing large conformational changes in the citrate domain that indirectly block the binding and recognition of citrate.
Molekulargewicht: 453.84
Reinheit: >99.0%
CAS Nummer: [2375840-87-0]
Formel: C20H14ClF2NO5S
Target-Kategorie: ATPase