NDI-091143, CAS [[2375840-87-0]]

Product Overview

• Article Name: NDI-091143, CAS [[2375840-87-0]]
• Biozol Catalog Number: AMO-M9587
• Supplier Catalog Number: M9587
• Alternative Catalog Number: AMO-M9587-2MG,AMO-M9587-5MG,AMO-M9587-10MG,AMO-M9587-25MG
• Manufacturer: Abmole Bioscience
• Category: Biochemikalien

Product Description

NDI-091143 is a novel potent inhibitor of human ATP-citrate lyase with an IC50 of 2.1 nM (ADP-Glo assay), a Ki of 7.0 nM and a Kd of 2.2 nM. NDI-091143 inhibits ACLY catalysis allosterically, by stabilizing large conformational changes in the citrate domain that indirectly block the binding and recognition of citrate.

Product Properties

• Molecular Weight: 453.84
• Purity: >99.0%
• CAS Number: [2375840-87-0]
• Formula: C20H14ClF2NO5S
• Target: ATPase