Sitravatinib, CAS [[1123837-84-2]]

Produktübersicht

• Artikelname: Sitravatinib, CAS [[1123837-84-2]]
• Artikelnummer: AMO-M9626
• Hersteller Artikelnummer: M9626
• Alternativnummer: AMO-M9626-5MG,AMO-M9626-10MG,AMO-M9626-25MG
• Hersteller: Abmole Bioscience
• Kategorie: Biochemikalien
• Alternative Synonym: MGCD516, MG516

Produktbeschreibung

Sitravatinib (MGCD516) is an orally active receptor tyrosine kinase (RTK) inhibitor. Inhibition of Axl, MER, VEGFR3, VEGFR2, VEGFR1, KIT, FLT3, DDR2, DDR1, TRKA, and TRKB at 1.5 nM, 2 nM, 2 nM, 5 nM, 6 nM, 6 nM, 8 nM, 0.5 nM, respectively. 29 nM, 5 nM and 9 nM. Sitravatinib alone has a potent antitumor effect and enhances pD-1 blockade activity by promoting the antitumor immune microenvironment.

Produkteigenschaften

• Molekulargewicht: 629.68
• Reinheit: 100.0%
• CAS Nummer: [1123837-84-2]
• Formel: C33H29F2N5O4S
• Target-Kategorie: VEGFR/PDGFR