Sitravatinib, CAS [[1123837-84-2]]
Catalog Number:
AMO-M9626
| Article Name: |
Sitravatinib, CAS [[1123837-84-2]] |
| Biozol Catalog Number: |
AMO-M9626 |
| Supplier Catalog Number: |
M9626 |
| Alternative Catalog Number: |
AMO-M9626-5MG,AMO-M9626-10MG,AMO-M9626-25MG |
| Manufacturer: |
Abmole Bioscience |
| Category: |
Biochemikalien |
| Alternative Names: |
MGCD516, MG516 |
| Sitravatinib (MGCD516) is an orally active receptor tyrosine kinase (RTK) inhibitor. Inhibition of Axl, MER, VEGFR3, VEGFR2, VEGFR1, KIT, FLT3, DDR2, DDR1, TRKA, and TRKB at 1.5 nM, 2 nM, 2 nM, 5 nM, 6 nM, 6 nM, 8 nM, 0.5 nM, respectively. 29 nM, 5 nM and 9 nM. Sitravatinib alone has a potent antitumor effect and enhances pD-1 blockade activity by promoting the antitumor immune microenvironment. |
| Molecular Weight: |
629.68 |
| Purity: |
100.0% |
| CAS Number: |
[1123837-84-2] |
| Formula: |
C33H29F2N5O4S |
| Target: |
VEGFR/PDGFR |
