Phospho-Src (Tyr419) Rabbit Polyclonal Antibody, Unconjugated
Catalog Number:
EKL-APRAB00684
Product Overview
Article Name:
Phospho-Src (Tyr419) Rabbit Polyclonal Antibody, Unconjugated
Biozol Catalog Number:
EKL-APRAB00684
Supplier Catalog Number:
APRab00684
Alternative Catalog Number:
EKL-APRAB00684-20UL, EKL-APRAB00684-50UL, EKL-APRAB00684-100UL, EKL-APRAB00684-200UL
Manufacturer:
EnkiLife
Host:
Rabbit
Category:
Antikörper
Application:
FC, WB
Species Reactivity:
Human, Mouse, Rat
Conjugation:
Unconjugated
Alternative Names:
SRC, SRC1, Proto-oncogene tyrosine-protein kinase Src, Proto-oncogene c-Src, pp60c-src, p60-Src
Product Description
Src activity is regulated by tyrosine phosphorylation at two sites, but with opposing effects. While phosphorylation at Tyr416 in the activation loop of the kinase domain upregulates enzyme activity, phosphorylation at Tyr527 in the carboxy-terminal tail by Csk renders the enzyme less active (2).
Product Properties
Clonality:
Polyclonal
Molecular Weight:
Calculated MW: 60 kDa, Observed MW: 60 kDa
NCBI:
6714
UniProt:
P12931
Buffer:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity:
Affinity Chromatography
Form:
Liquid
Target:
SRC
Application Notes
Application Dilute:
WB 1:500-1:1000,FC 1:50-1:100