Addressing the reproducibility crisis Validating antibodies for life science research

In this webinar, you can learn about the Human Protein Atlas approach for validating antibodies for life science research, and about the five methods used in enhanced validation. The webinar was recorded on April 11, 2018, hosted by Science and sponsored by Atlas Antibodies.  It features Professor Mathias Uhl&ea...

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Building DNA Libraries Explore the Combinatorial Design Space

Engineering complex biological systems is not straightforward. To this end, synthetic biologists often need to explore a combinatorial design space to achieve the best performance. In this webinar, we will discuss strategies for designing and assembling combinatorial DNA libraries to optimize or develop novel metabolic pathways, genetic circuits, or microbial strains. We will also introduce our comprehensive combinatorial DNA library services, which can greatly accelerate the build phase of your development cycle and facilitate your engineering of nov...

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Cell Fractionation Characterizing B cells and Their Antibodies using Single-Cell RNA Sequ...

The study of single cells has provided insights into the composition and function of an increasing number of biological systems across both health and disease. Single-cell RNA sequencing (scRNA-seq) is a particularly powerful approach that can provide the subtype, transcriptional state, and antibody sequence of single B cells.

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CRISPR Cas9 genome-editing Essential Guide to Becoming a CRISPR Cas9 Expert

The ability to precisely edit and change any part of an organism’s genome has long been sought by scientists, and today, we are closer to that goal than ever before. With the discovery of the CRISPR Cas9 system, scientists are now able to effortlessly and efficiently knock-out or knock-in any gene of interest. Given its ease of...

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Cygnus AAE™ - MS services Determination of anti-HCP coverage

Host cell proteins (HCPs) are process-related impurities, expressed by the host cell used for production of biopharmaceutical proteins. While the majority of these HCPs are removed during the purification process, there are still residual HCP amounts remaining in the distributed products, with unknown effects on protein stability or immunogenicity in the patients....

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Detecting Cell Death Apoptosis, Pyroptosis, Autophagy, and Necrosis

Cell death is a critical and unavoidable part of life. From the quiet turnover of worn out cells and cellular components to the inflammatory death that warns of infection, cell death is involved in countless areas of scientific research. ImmunoChemistry Technologies offers many tools for studying cell death pathways, including their...

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ELISA Benefits of Sample and Assay Diluents

Nonspecific binding interactions, sample variation, background noise, and matrix interference are all common problems encountered when performing ELISA testing. ICT offers a range of diluent options designed to help overcome these issues. ICT’s Sample Diluents are used to dilute ELISA test samples so they read within the functional range of the assay. Our Assay Diluents are added to all wells of the plate to equalize any differences between the sample matrix and the diluent used to generate the standard curve. The right sample diluent can aid in...

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Flow Cytometry Analysis Infinicyt™ 2.0: Get Started

Infinicyt™ 2.0 is Cytognos' flow cytometry software, based on Euroflow™ LST and PIDOT databases.   Features of the newest version: Clustering Analysis Maturation Compensation Matrix Diagrams Population Tree & S...

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Lateral Flow A Guide to Lateral Flow Immunoassay Development

This latest presentation on lateral flow immunoassay development will provide a general overview of lateral flow assays, take you through the components of a typical lateral flow test strip, and will provide you with detail on the different detection methods which are employed. It also describes how Expedeons products and custom serv...

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Next Generation Sequencing (NGS) An introduction by ABM

Deoxyribonucleic acid, commonly known as DNA, contains the blueprints of life. Within its structures are the codes required for the assembly of proteins and non-coding RNA – these molecular machineries affect all the biological systems that create and maintain life. By understanding the sequence of DNA, researchers have been able to elucidate the structure and function of proteins...

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