Securin polyclonal antibody, Unconjugated, Rabbit
Catalog Number:
BWT-BZ16895
Product Overview
Article Name:
Securin polyclonal antibody, Unconjugated, Rabbit
Biozol Catalog Number:
BWT-BZ16895
Supplier Catalog Number:
BZ16895
Alternative Catalog Number:
BWT-BZ16895-50UL,BWT-BZ16895-100UL
Manufacturer:
Bioworld Technology
Host:
Rabbit
Category:
Antikörper
Application:
FC, ICC, IHC-P, IP, WB
Species Reactivity:
Human
Immunogen:
A synthesized peptide derived from human Securin
Conjugation:
Unconjugated
Alternative Names:
PTTG1, EAP1, PTTG, TUTR1, Securin, Esp1-associated protein, Pituitary tumor-transforming gene 1 protein, Tumor-transforming protein 1, hPTTG
Product Description
Regulatory protein, which plays a central role in chromosome stability, in the p53/TP53 pathway, and DNA repair. Probably acts by blocking the action of key proteins. During the mitosis, it blocks Separase/ESPL1 function, preventing the proteolysis of the cohesin complex and the subsequent segregation of the chromosomes.
Product Properties
Molecular Weight:
Calculated MW: 22 kDa, Observed MW: 28 kDa
UniProt:
O95997
Purity:
Affinity Purified
Form:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Application Notes
Application Dilute:
WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20 FC: 1/50-1/100
Application Notes:
IgG
