RAD17 Antibody - N-terminal region

Produktübersicht

• Artikelname: RAD17 Antibody - N-terminal region
• Artikelnummer: ASB-ARP30546_P050
• Hersteller Artikelnummer: ARP30546_P050
• Alternativnummer: ASB-ARP30546_P050-25UL,ASB-ARP30546_P050-100UL
• Hersteller: Aviva
• Wirt: Rabbit
• Kategorie: Proteine/Peptide
• Applikation: WB
• Spezies Reaktivität: Bovine, Canine, Equine, Human, Porcine, Rabbit, Rat
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RAD17
• Alternative Synonym: CCYC, R24L, RAD24, HRAD17, RAD17SP

Produktbeschreibung

RAD17 is highly similar to the gene product of Schizosaccharomyces pombe rad17, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein shares strong similarity with DNA replication factor C (RFC), and can form a complex with RFCs. This protein binds to chromatin prior to DNA damage and is phosphorylated by ATR after the damage. This protein recruits the RAD1-RAD9-HUS1 checkpoint protein complex onto chromatin after DNA damage, which may be required for its phosphorylation.

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 0.5 mg/ml
• Molekulargewicht: 76kDa
• NCBI: 5884
• UniProt: O75943-2
• Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.