RAD17 Antibody - N-terminal region

Product Overview

• Article Name: RAD17 Antibody - N-terminal region
• Biozol Catalog Number: ASB-ARP30546_P050
• Supplier Catalog Number: ARP30546_P050
• Alternative Catalog Number: ASB-ARP30546_P050-25UL,ASB-ARP30546_P050-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: WB
• Species Reactivity: Bovine, Canine, Equine, Human, Porcine, Rabbit, Rat
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RAD17
• Alternative Names: CCYC, R24L, RAD24, HRAD17, RAD17SP

Product Description

RAD17 is highly similar to the gene product of Schizosaccharomyces pombe rad17, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein shares strong similarity with DNA replication factor C (RFC), and can form a complex with RFCs. This protein binds to chromatin prior to DNA damage and is phosphorylated by ATR after the damage. This protein recruits the RAD1-RAD9-HUS1 checkpoint protein complex onto chromatin after DNA damage, which may be required for its phosphorylation.

Product Properties

• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Molecular Weight: 76kDa
• NCBI: 5884
• UniProt: O75943-2
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.