POU4F3 Antibody - middle region
Artikelnummer:
ASB-ARP33065_T100
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| Artikelname: | POU4F3 Antibody - middle region |
| Artikelnummer: | ASB-ARP33065_T100 |
| Hersteller Artikelnummer: | ARP33065_T100 |
| Alternativnummer: | ASB-ARP33065_T100-25UL,ASB-ARP33065_T100-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | IHC, WB |
| Spezies Reaktivität: | Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish |
| Immunogen: | The immunogen is a synthetic peptide directed towards the middle region of human POU4F3 |
| Alternative Synonym: | BRN3C, DFNA15, DFNA42, DFNA52 |
| POU4F3 is capable of activating both BDNF and NT-3 promoters in inner ear sensory epithelial cell lines. Mutant POU4F3 loses most of its transcriptional activity and most of its ability to bind to DNA. The mutation causes autosomal-dominant nonsyndromic hearing loss and eventually leads to hair cell morbidity in affected family members. |
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