POU4F3 Antibody - middle region

Product Overview

• Article Name: POU4F3 Antibody - middle region
• Biozol Catalog Number: ASB-ARP33065_T100
• Supplier Catalog Number: ARP33065_T100
• Alternative Catalog Number: ASB-ARP33065_T100-25UL,ASB-ARP33065_T100-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: IHC, WB
• Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human POU4F3
• Alternative Names: BRN3C, DFNA15, DFNA42, DFNA52

Product Description

POU4F3 is capable of activating both BDNF and NT-3 promoters in inner ear sensory epithelial cell lines. Mutant POU4F3 loses most of its transcriptional activity and most of its ability to bind to DNA. The mutation causes autosomal-dominant nonsyndromic hearing loss and eventually leads to hair cell morbidity in affected family members.

Product Properties

• Clonality: Polyclonal
• Concentration: 1.0 mg/ml
• Molecular Weight: 37kDa
• NCBI: 5459
• UniProt: Q15319
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.