KCNIP2 Antibody - N-terminal region

Produktübersicht

• Artikelname: KCNIP2 Antibody - N-terminal region
• Artikelnummer: ASB-ARP35491_P050
• Hersteller Artikelnummer: ARP35491_P050
• Alternativnummer: ASB-ARP35491_P050-25UL,ASB-ARP35491_P050-100UL
• Hersteller: Aviva
• Wirt: Rabbit
• Kategorie: Proteine/Peptide
• Applikation: WB
• Spezies Reaktivität: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human KCNIP2
• Alternative Synonym: KCHIP2

Produktbeschreibung

KCNIP2 encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belongs to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belongs to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified from this gene.

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 0.5 mg/ml
• Molekulargewicht: 32kDa
• NCBI: 30819
• UniProt: Q9NS61-6
• Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Bilder

Rabbit Anti-KCNIP2 antibody
Catalog Number: ARP35491
Formalin Fixed Paraffin Embedded Tissue: Human Heart
Primary antibody Concentration: 1:100
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20x
Exposure Time: 0.5-2.0sec

WB Suggested Anti-KCNIP2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Jurkat cell lysateKCNIP2 is supported by BioGPS gene expression data to be expressed in Jurkat

Lanes:
Lane 1: 20ug HEK-293 cell lysate
Lane 2: 20ug mkchIP2-YFP transfected HEK-293 lysate
Lane 3: 20ug mkchIP3-YFP transfected HEK-293 lysate
Lane 4: 20ug mkchIP4-YFP transfected HEK-293 lysate
Primary Antibody Dilution:
1:1000
Secondary Antibody:
Donkey anti-rabbit-HRP
Secondary Antibody Dilution:
1:10,000
Gene Name:
KCNIP2
Submitted by:
Jeanne M. Nerbonne, Arvin Soepriatna, Washington University Medical School Department of Developmental Biology

Host: Rabbit
Target Name: KCNIP2
Sample Type: Human Jurkat
Antibody Dilution: 1.0ug/mlKCNIP2 is supported by BioGPS gene expression data to be expressed in Jurkat

Host: Rabbit
Target Name: KCNIP2
Sample Type: Human Fetal Brain
Antibody Dilution: 1.0ug/ml

KCNIP2 antibody - N-terminal region (ARP35491_P050) in Human Jurkat using Western Blot