Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish
Immunogen:
The immunogen is a synthetic peptide directed towards the N terminal region of human KCNIP2
Alternative Names:
KCHIP2
KCNIP2 encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belongs to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belongs to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified from this gene.
WB Suggested Anti-KCNIP2 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: Jurkat cell lysateKCNIP2 is supported by BioGPS gene expression data to be expressed in Jurkat
Lanes: Lane 1: 20ug HEK-293 cell lysate Lane 2: 20ug mkchIP2-YFP transfected HEK-293 lysate Lane 3: 20ug mkchIP3-YFP transfected HEK-293 lysate Lane 4: 20ug mkchIP4-YFP transfected HEK-293 lysate Primary Antibody Dilution: 1:1000 Secondary Antibody: Donkey anti-rabbit-HRP Secondary Antibody Dilution: 1:10,000 Gene Name: KCNIP2 Submitted by: Jeanne M. Nerbonne, Arvin Soepriatna, Washington University Medical School Department of Developmental Biology
Host: Rabbit Target Name: KCNIP2 Sample Type: Human Jurkat Antibody Dilution: 1.0ug/mlKCNIP2 is supported by BioGPS gene expression data to be expressed in Jurkat