Bovine, Canine, Equine, Human, Mouse, Porcine, Rabbit, Rat, Zebrafish
Immunogen:
The immunogen is a synthetic peptide directed towards the middle region of human ONECUT1
Alternative Synonym:
HNF6, HNF-6, HNF6A
ONECUT1 belongs to the CUT homeobox family. It contains 1 CUT DNA-binding domain and 1 homeobox DNA-binding domain. It is a transcriptional activator. ONECUT1 binds the consensus sequence 5-DHWATTGAYTWWD-3 on a variety of gene promoters such as those of HNF3B and TTR. It is important for liver genes transcription.