IKZF3 Antibody - middle region, Rabbit, Polyclonal
Artikelnummer:
ASB-ARP39702_P050
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| Artikelname: | IKZF3 Antibody - middle region, Rabbit, Polyclonal |
| Artikelnummer: | ASB-ARP39702_P050 |
| Hersteller Artikelnummer: | ARP39702_P050 |
| Alternativnummer: | ASB-ARP39702_P050-25UL,ASB-ARP39702_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Antikörper |
| Applikation: | WB |
| Spezies Reaktivität: | Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Yeast |
| Immunogen: | The immunogen is a synthetic peptide directed towards the middle region of Human IKZF3 |
| Alternative Synonym: | AIO, AIOLOS, ZNFN1A3 |
| IKZF3 is a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoetic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. At least six alternative transcripts encoding different isoforms have been described. |
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