IKZF3 Antibody - middle region, Rabbit, Polyclonal

Product Overview

• Article Name: IKZF3 Antibody - middle region, Rabbit, Polyclonal
• Biozol Catalog Number: ASB-ARP39702_P050
• Supplier Catalog Number: ARP39702_P050
• Alternative Catalog Number: ASB-ARP39702_P050-25UL,ASB-ARP39702_P050-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Antikörper
• Application: WB
• Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Yeast
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human IKZF3
• Alternative Names: AIO, AIOLOS, ZNFN1A3

Product Description

IKZF3 is a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoetic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. At least six alternative transcripts encoding different isoforms have been described.

Product Properties

• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Molecular Weight: 28kDa
• NCBI: 22806
• UniProt: Q9UKT9-14
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.