ZNF496 Antibody - N-terminal region, Rabbit, Polyclonal
Artikelnummer:
ASB-ARP39715_T100
- Bilder (0)
| Artikelname: | ZNF496 Antibody - N-terminal region, Rabbit, Polyclonal |
| Artikelnummer: | ASB-ARP39715_T100 |
| Hersteller Artikelnummer: | ARP39715_T100 |
| Alternativnummer: | ASB-ARP39715_T100-25UL,ASB-ARP39715_T100-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Antikörper |
| Applikation: | WB |
| Spezies Reaktivität: | Bovine, Canine, Equine, Guinea pig, Human, Mouse, Porcine, Rabbit, Rat, Sheep |
| Immunogen: | The immunogen is a synthetic peptide directed towards the N terminal region of human ZNF496 |
| Alternative Synonym: | NIZP1, ZFP496, ZSCAN49, ZKSCAN17 |
| ZNF496 contains a SCAN box, a KRAB-A domain, and four consensus C2H2-type zinc fingers preceded by a unique finger derivative, referred to herein as the C2HR motif. The C2HR motif functions to mediate protein-protein interaction with the cysteine-rich (C5HCH) domain of NSD1 in a Zn(II)-dependent fashion, and when tethered to RNA polymerase II promoters, represses transcription in an NSD1-dependent manner. ZNF496 contains a novel type of zinc finger motif that functions as a docking site for NSD1 and is more than just a degenerate evolutionary remnant of a C2H2 motif. |
Produktgarantie und fachkundiger Support
