ZNF496 Antibody - N-terminal region, Rabbit, Polyclonal

Product Overview

• Article Name: ZNF496 Antibody - N-terminal region, Rabbit, Polyclonal
• Biozol Catalog Number: ASB-ARP39715_T100
• Supplier Catalog Number: ARP39715_T100
• Alternative Catalog Number: ASB-ARP39715_T100-25UL,ASB-ARP39715_T100-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Antikörper
• Application: WB
• Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Porcine, Rabbit, Rat, Sheep
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ZNF496
• Alternative Names: NIZP1, ZFP496, ZSCAN49, ZKSCAN17

Product Description

ZNF496 contains a SCAN box, a KRAB-A domain, and four consensus C2H2-type zinc fingers preceded by a unique finger derivative, referred to herein as the C2HR motif. The C2HR motif functions to mediate protein-protein interaction with the cysteine-rich (C5HCH) domain of NSD1 in a Zn(II)-dependent fashion, and when tethered to RNA polymerase II promoters, represses transcription in an NSD1-dependent manner. ZNF496 contains a novel type of zinc finger motif that functions as a docking site for NSD1 and is more than just a degenerate evolutionary remnant of a C2H2 motif.

Product Properties

• Clonality: Polyclonal
• Concentration: 1.0 mg/ml
• Molecular Weight: 67kDa
• NCBI: 84838
• UniProt: Q96IT1
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.