HIF3A Antibody - C-terminal region

Produktübersicht

• Artikelname: HIF3A Antibody - C-terminal region
• Artikelnummer: ASB-ARP39936_T100
• Hersteller Artikelnummer: ARP39936_T100
• Alternativnummer: ASB-ARP39936_T100-25UL,ASB-ARP39936_T100-100UL
• Hersteller: Aviva
• Wirt: Rabbit
• Kategorie: Proteine/Peptide
• Applikation: IHC, WB
• Spezies Reaktivität: Human
• Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human HIF3A
• Alternative Synonym: IPAS, MOP7, PASD7, HIF-3A, bHLHe17, HIF3-alpha-1

Produktbeschreibung

HIF3A is the alpha-3 subunit of one of several alpha/beta-subunit heterodimeric transcription factors that regulate many adaptive responses to low oxygen tension (hypoxia). The alpha-3 subunit lacks the transactivation domain found in factors containing either the alpha-1 or alpha-2 subunits. It is thought that factors containing the alpha-3 subunit are negative regulators of hypoxia-inducible gene expression.The protein encoded by this gene is the alpha-3 subunit of one of several alpha/beta-subunit heterodimeric transcription factors that regulate many adaptive responses to low oxygen tension (hypoxia). The alpha-3 subunit lacks the transactivation domain found in factors containing either the alpha-1 or alpha-2 subunits. It is thought that factors containing the alpha-3 subunit are negative regulators of hypoxia-inducible gene expression. At least three transcript variants encoding three different isoforms have been found for this gene.

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 1.0 mg/ml
• Molekulargewicht: 72 kDa
• NCBI: 64344
• UniProt: Q9Y2N7
• Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Bilder

Human kidney

WB Suggested Anti-HIF3A Antibody Titration: 1.25ug/ml
Positive Control: HepG2 cell lysateThere is BioGPS gene expression data showing that HIF3A is expressed in HepG2

25 ug of the indicated Human whole cell extracts was loaded onto a 12% SDS-PAGE gel. 3 ug/mL of the antibody was used in this experiment. Multiple isoforms from 83 kDa to 65 kDa contain the immunizing peptide. Recommended dilution for this antibody is 1-3 ug/mL.

0