HIF3A Antibody - C-terminal region

Product Overview

• Article Name: HIF3A Antibody - C-terminal region
• Biozol Catalog Number: ASB-ARP39936_T100
• Supplier Catalog Number: ARP39936_T100
• Alternative Catalog Number: ASB-ARP39936_T100-25UL,ASB-ARP39936_T100-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: IHC, WB
• Species Reactivity: Human
• Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human HIF3A
• Alternative Names: IPAS, MOP7, PASD7, HIF-3A, bHLHe17, HIF3-alpha-1

Product Description

HIF3A is the alpha-3 subunit of one of several alpha/beta-subunit heterodimeric transcription factors that regulate many adaptive responses to low oxygen tension (hypoxia). The alpha-3 subunit lacks the transactivation domain found in factors containing either the alpha-1 or alpha-2 subunits. It is thought that factors containing the alpha-3 subunit are negative regulators of hypoxia-inducible gene expression.The protein encoded by this gene is the alpha-3 subunit of one of several alpha/beta-subunit heterodimeric transcription factors that regulate many adaptive responses to low oxygen tension (hypoxia). The alpha-3 subunit lacks the transactivation domain found in factors containing either the alpha-1 or alpha-2 subunits. It is thought that factors containing the alpha-3 subunit are negative regulators of hypoxia-inducible gene expression. At least three transcript variants encoding three different isoforms have been found for this gene.

Product Properties

• Clonality: Polyclonal
• Concentration: 1.0 mg/ml
• Molecular Weight: 72 kDa
• NCBI: 64344
• UniProt: Q9Y2N7
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Images

Human kidney

WB Suggested Anti-HIF3A Antibody Titration: 1.25ug/ml
Positive Control: HepG2 cell lysateThere is BioGPS gene expression data showing that HIF3A is expressed in HepG2

25 ug of the indicated Human whole cell extracts was loaded onto a 12% SDS-PAGE gel. 3 ug/mL of the antibody was used in this experiment. Multiple isoforms from 83 kDa to 65 kDa contain the immunizing peptide. Recommended dilution for this antibody is 1-3 ug/mL.

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