NR3C1 Antibody - N-terminal region

Produktübersicht

• Artikelname: NR3C1 Antibody - N-terminal region
• Artikelnummer: ASB-ARP45593_P050
• Hersteller Artikelnummer: ARP45593_P050
• Alternativnummer: ASB-ARP45593_P050-25UL,ASB-ARP45593_P050-100UL
• Hersteller: Aviva
• Wirt: Rabbit
• Kategorie: Proteine/Peptide
• Applikation: IHC, WB
• Spezies Reaktivität: Bovine, Equine, Guinea pig, Human, Mouse, Porcine, Rat
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human NR3C1
• Alternative Synonym: GR, GCR, GRL, GCCR, GCRST

Produktbeschreibung

NR3C1 is a receptor for glucocorticoids that can act as both a transcription factor and as a regulator of other transcription factors. This protein can also be found in heteromeric cytoplasmic complexes along with heat shock factors and immunophilins. The protein is typically found in the cytoplasm until it binds a ligand, which induces transport into the nucleus. Mutations in this gene are a cause of glucocorticoid resistance, or cortisol, resistance. The protein encoded by this gene is a receptor for glucocorticoids that can act as both a transcription factor and as a regulator of other transcription factors. This protein can also be found in heteromeric cytoplasmic complexes along with heat shock factors and immunophilins. The protein is typically found in the cytoplasm until it binds a ligand, which induces transport into the nucleus. Mutations in this gene are a cause of glucocorticoid resistance, or cortisol, resistance. Alternate splicing, the use of at least three different promoters, and alternate translation initiation sites result in several transcript variants encoding the same protein or different isoforms, but the full-length nature of some variants has not been determined.

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 0.5 mg/ml
• Molekulargewicht: 86kDa
• NCBI: 2908
• UniProt: P04150
• Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Bilder

Colon, submucosal plexus

WB Suggested Anti-NR3C1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Hela cell lysateNR3C1 is strongly supported by BioGPS gene expression data to be expressed in Human HeLa cells

Host: Rabbit
Target Name: NR3C1
Sample Type: Hela
Antibody Dilution: 1.0ug/ml

NR3C1 antibody - N-terminal region (ARP45593_P050) in Human HeLa using Western Blot