NR3C1 Antibody - N-terminal region
Catalog Number:
ASB-ARP45593_P050
- Images (4)
| Article Name: | NR3C1 Antibody - N-terminal region |
| Biozol Catalog Number: | ASB-ARP45593_P050 |
| Supplier Catalog Number: | ARP45593_P050 |
| Alternative Catalog Number: | ASB-ARP45593_P050-25UL,ASB-ARP45593_P050-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | IHC, WB |
| Species Reactivity: | Bovine, Equine, Guinea pig, Human, Mouse, Porcine, Rat |
| Immunogen: | The immunogen is a synthetic peptide directed towards the N terminal region of human NR3C1 |
| Alternative Names: | GR, GCR, GRL, GCCR, GCRST |
| NR3C1 is a receptor for glucocorticoids that can act as both a transcription factor and as a regulator of other transcription factors. This protein can also be found in heteromeric cytoplasmic complexes along with heat shock factors and immunophilins. The protein is typically found in the cytoplasm until it binds a ligand, which induces transport into the nucleus. Mutations in this gene are a cause of glucocorticoid resistance, or cortisol, resistance. The protein encoded by this gene is a receptor for glucocorticoids that can act as both a transcription factor and as a regulator of other transcription factors. This protein can also be found in heteromeric cytoplasmic complexes along with heat shock factors and immunophilins. The protein is typically found in the cytoplasm until it binds a ligand, which induces transport into the nucleus. Mutations in this gene are a cause of glucocorticoid resistance, or cortisol, resistance. Alternate splicing, the use of at least three different promoters, and alternate translation initiation sites result in several transcript variants encoding the same protein or different isoforms, but the full-length nature of some variants has not been determined. |
|
|
Colon, submucosal plexus |
|
|
WB Suggested Anti-NR3C1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Positive Control: Hela cell lysateNR3C1 is strongly supported by BioGPS gene expression data to be expressed in Human HeLa cells |
|
|
Host: Rabbit Target Name: NR3C1 Sample Type: Hela Antibody Dilution: 1.0ug/ml |
|
|
NR3C1 antibody - N-terminal region (ARP45593_P050) in Human HeLa using Western Blot |
Product Guarantee and Expert Support
