IMPDH2 Antibody - N-terminal region

Artikelnummer: ASB-ARP54365_P050
Artikelname: IMPDH2 Antibody - N-terminal region
Artikelnummer: ASB-ARP54365_P050
Hersteller Artikelnummer: ARP54365_P050
Alternativnummer: ASB-ARP54365_P050-25UL,ASB-ARP54365_P050-100UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: IHC, WB
Spezies Reaktivität: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human IMPDH2
Alternative Synonym: IMPD2, IMPDH-II
IMPDH2 is the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. It catalyzes the NAD-dependent oxidation of inosine-5-monophosphate into xanthine-5-monophosphate, which is then converted into guanosine-5-monophosphate. IMPDH2 is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation.
Klonalität: Polyclonal
Konzentration: 0.5 mg/ml
Molekulargewicht: 56 kDa
NCBI: 3615
UniProt: P12268
Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
25 ug of the indicated Human whole cell extracts was loaded onto a 12% SDS-PAGE gel. 1 ug/mL of the antibody was used in this experiment. The protein may be modified by glycosylation and phosphorylation.
Sample Type:
Human Hep-2 cellsPrimary Antibody Dilution:
1:500Secondary Antibody:
Goat anti-rabbit-Alexa Fluor 568Secondary Antibody Dilution:
1:400Color/Signal Descriptions:
Red: IMPDH2 Blue: DAPIGene Name:
IMPDH2Submitted by:
S. John Calise, Edward Chan Lab, University of Florida
WB Suggested Anti-IMPDH2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: 721_B cell lysateIMPDH2 is supported by BioGPS gene expression data to be expressed in 721_B
Host: Rabbit
Target Name: IMPDH2
Sample Tissue: Human Jurkat Whole Cell
Antibody Dilution: 3ug/ml
IMPDH2 antibody - N-terminal region (ARP54365_P050) in Human 721_B using Western Blot