IMPDH2 Antibody - N-terminal region

Product Overview

• Article Name: IMPDH2 Antibody - N-terminal region
• Biozol Catalog Number: ASB-ARP54365_P050
• Supplier Catalog Number: ARP54365_P050
• Alternative Catalog Number: ASB-ARP54365_P050-25UL,ASB-ARP54365_P050-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: IHC, WB
• Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human IMPDH2
• Alternative Names: IMPD2, IMPDH-II

Product Description

IMPDH2 is the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. It catalyzes the NAD-dependent oxidation of inosine-5-monophosphate into xanthine-5-monophosphate, which is then converted into guanosine-5-monophosphate. IMPDH2 is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation.

Product Properties

• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Molecular Weight: 56 kDa
• NCBI: 3615
• UniProt: P12268
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Images

25 ug of the indicated Human whole cell extracts was loaded onto a 12% SDS-PAGE gel. 1 ug/mL of the antibody was used in this experiment. The protein may be modified by glycosylation and phosphorylation.

Sample Type:
Human Hep-2 cellsPrimary Antibody Dilution:
1:500Secondary Antibody:
Goat anti-rabbit-Alexa Fluor 568Secondary Antibody Dilution:
1:400Color/Signal Descriptions:
Red: IMPDH2 Blue: DAPIGene Name:
IMPDH2Submitted by:
S. John Calise, Edward Chan Lab, University of Florida

WB Suggested Anti-IMPDH2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: 721_B cell lysateIMPDH2 is supported by BioGPS gene expression data to be expressed in 721_B

Host: Rabbit
Target Name: IMPDH2
Sample Tissue: Human Jurkat Whole Cell
Antibody Dilution: 3ug/ml

IMPDH2 antibody - N-terminal region (ARP54365_P050) in Human 721_B using Western Blot