CYBB Antibody - C-terminal region

Produktübersicht

• Artikelname: CYBB Antibody - C-terminal region
• Artikelnummer: ASB-ARP70865_P050
• Hersteller Artikelnummer: ARP70865_P050
• Alternativnummer: ASB-ARP70865_P050-25UL,ASB-ARP70865_P050-100UL
• Hersteller: Aviva
• Wirt: Rabbit
• Kategorie: Proteine/Peptide
• Applikation: WB
• Spezies Reaktivität: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat
• Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human CYBB
• Alternative Synonym: CGD, NOX2, IMD34, AMCBX2, GP91-1, GP91PHOX, p91-PHOX, GP91-PHOX

Produktbeschreibung

Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase, neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cells respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole.

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 0.5 mg/ml
• Molekulargewicht: 65kDa
• NCBI: 1536
• UniProt: P04839
• Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Bilder

Host: Rabbit
Target Name: CY24B
Sample Type: 721_B Whole Cell lysates
Antibody Dilution: 1.0ug/ml

Host: Rabbit
Target Name: CYBB
Sample Type: 721_B Whole Cell lysates
Antibody Dilution: 1.0ug/ml

Host: Rabbit
Target Name: CY24B
Sample Type: 721_B Whole Cell lysates
Antibody Dilution: 1ug/ml

Host: Rabbit
Target Name: CYBB
Sample Tissue: Human Jurkat
Antibody Dilution: 1.0ug/ml

CYBB Antibody - C-terminal region (ARP70865_P050) in Human Jurkat using Western Blot