CYBB Antibody - C-terminal region

Product Overview

• Article Name: CYBB Antibody - C-terminal region
• Biozol Catalog Number: ASB-ARP70865_P050
• Supplier Catalog Number: ARP70865_P050
• Alternative Catalog Number: ASB-ARP70865_P050-25UL,ASB-ARP70865_P050-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: WB
• Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat
• Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human CYBB
• Alternative Names: CGD, NOX2, IMD34, AMCBX2, GP91-1, GP91PHOX, p91-PHOX, GP91-PHOX

Product Description

Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase, neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cells respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole.

Product Properties

• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Molecular Weight: 65kDa
• NCBI: 1536
• UniProt: P04839
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Images

Host: Rabbit
Target Name: CY24B
Sample Type: 721_B Whole Cell lysates
Antibody Dilution: 1.0ug/ml

Host: Rabbit
Target Name: CYBB
Sample Type: 721_B Whole Cell lysates
Antibody Dilution: 1.0ug/ml

Host: Rabbit
Target Name: CY24B
Sample Type: 721_B Whole Cell lysates
Antibody Dilution: 1ug/ml

Host: Rabbit
Target Name: CYBB
Sample Tissue: Human Jurkat
Antibody Dilution: 1.0ug/ml

CYBB Antibody - C-terminal region (ARP70865_P050) in Human Jurkat using Western Blot