BBC3 Antibody - middle region
Artikelnummer:
ASB-ARP96868_P050
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| Artikelname: | BBC3 Antibody - middle region |
| Artikelnummer: | ASB-ARP96868_P050 |
| Hersteller Artikelnummer: | ARP96868_P050 |
| Alternativnummer: | ASB-ARP96868_P050-25UL,ASB-ARP96868_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | WB |
| Spezies Reaktivität: | Human |
| Immunogen: | The immunogen is a synthetic peptide directed towards the middle region of human BBC3 |
| Alternative Synonym: | JFY1, PUMA, JFY-1 |
| This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants. |
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