BBC3 Antibody - middle region
Catalog Number:
ASB-ARP96868_P050
- Images (0)
| Article Name: | BBC3 Antibody - middle region |
| Biozol Catalog Number: | ASB-ARP96868_P050 |
| Supplier Catalog Number: | ARP96868_P050 |
| Alternative Catalog Number: | ASB-ARP96868_P050-25UL,ASB-ARP96868_P050-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | WB |
| Species Reactivity: | Human |
| Immunogen: | The immunogen is a synthetic peptide directed towards the middle region of human BBC3 |
| Alternative Names: | JFY1, PUMA, JFY-1 |
| This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants. |
Product Guarantee and Expert Support
