ATG4B Antibody - C-terminal region
Artikelnummer:
ASB-ARP97039_P050
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| Artikelname: | ATG4B Antibody - C-terminal region |
| Artikelnummer: | ASB-ARP97039_P050 |
| Hersteller Artikelnummer: | ARP97039_P050 |
| Alternativnummer: | ASB-ARP97039_P050-25UL,ASB-ARP97039_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | WB |
| Spezies Reaktivität: | Human |
| Immunogen: | The immunogen is a synthetic peptide directed towards the C terminal region of human ATG4B |
| Alternative Synonym: | APG4B, AUTL1 |
| Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms. |
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