ATG4B Antibody - C-terminal region

Product Overview

• Article Name: ATG4B Antibody - C-terminal region
• Biozol Catalog Number: ASB-ARP97039_P050
• Supplier Catalog Number: ARP97039_P050
• Alternative Catalog Number: ASB-ARP97039_P050-25UL,ASB-ARP97039_P050-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: WB
• Species Reactivity: Human
• Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ATG4B
• Alternative Names: APG4B, AUTL1

Product Description

Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.

Product Properties

• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Molecular Weight: 37 kDa
• NCBI: 23192
• UniProt: Q9Y4P1-4
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.